Do you really need the endometrial receptivity array test (ERA)

Due to repeated implantation failures during IVF procedure patients become distressed. This situation also turns out to be complicated for IVF specialist who is performing all steps of IVF procedure carefully. In such situations, IVF specialist performs various tests to identify the sole reason behind implantation failure.

There are two main reasons for implantation failures are

  1. Genetic abnormalities- To identify genetic abnormalities, IVF specialist recommended certain genetic tests (PGD/PGS). These tests are performed on the embryo before implantation.

  2. Uterus problem- Sometimes, abnormality in uterus’s shape and structure/ lining may lead to implantation failure. In these situations, IVF specialist carries out various tests. Endometrial receptivity array (ERA) test is one of those tests.

What is Endometrial receptivity array (ERA) test?

Endometrium wall is a lining of tissues containing a certain class of genes. The thickness of endometrium increases during cycle and when it reaches its thickest state from 19 – 23 day of cycle. A thick endometrium state is valuable for proper implantation of the embryo and pregnancy. Therefore, it is very important for the successful implantation of the embryo to identify the correct time.

The ERA is a genetic test which helps to identify the accurate time to transfer the embryo inside woman uterus (womb) for successful implantation via genes analysis.

What does ERA test check?

Every woman has a different window of implantation in her monthly cycle. A window of implantation is defined as that period when the uterus is receptive for implantation of the embryo. This window is very short and occurs from 19 to 23 day of the cycle. According to few studies, 20% to 25 % patients have an abnormal window of implantation. In such conditions, IVF specialist performs the ERA test and result of this test helps to identify the time to transfer embryo.

How accurate is ERA test?

Currently, ERA is the most reliable and accurate test available to identify the right time to transfer embryo inside the womb. This test is used for diagnosis of altered window of implantation. Therefore, this test has been established to provide accurate time for each patient for the successful implantation of the embryo.

How is really ERA test useful?

ERA test result helps to identify the right time of embryo transfer and improves the reproductive performance in the patients. Its role is however limited to women with recurrent as well as unexplained implantation and multiple IVF failures.

Some studies conclude that ERA test result helps to improve pregnancy rate up to 85% globally in those who are suffering from repeated implantation failure during IVF.

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